Mebendazole is a widely used antiparasitic medication effective against a range of intestinal worm infections. It belongs to the benzimidazole class of drugs and works by disrupting the worms' ability to absorb glucose, their primary energy source. This starvation mechanism ultimately leads to the death of the parasites.
Mebendazole 100 mg is prescribed for infections caused by common roundworms (Ascaris lumbricoides), hookworms (Ancylostoma duodenale, Necator americanus), whipworms (Trichuris trichiura), and pinworms (Enterobius vermicularis). For pinworm infections, a single 100 mg dose is often sufficient, though a repeat dose after two weeks may be recommended to prevent reinfection, as the medication does not kill worm eggs. For other common worm infections, the typical dosage is 100 mg taken twice daily for three consecutive days. In some cases, particularly for certain types of worm infections or if a cure is not achieved, a second course of treatment may be necessary.
It's crucial to follow the prescribed dosage and duration, even if symptoms improve, to ensure complete eradication of the parasite. Mebendazole is generally well-tolerated, but common side effects can include stomach pain, nausea, and diarrhea. Good hygiene practices, such as frequent handwashing, are also vital to prevent reinfection and the spread of parasites.