Skill interactions and support gems play a significant role in enhancing curse builds. Many curse skills can be modified with increased area of effect, duration, or effectiveness, allowing multiple enemies to be affected simultaneously. Certain support gems even enable additional curse applications, ensuring that players can stack multiple curses on a single target for compounding effects. This flexibility encourages experimentation, as players can tailor curse setups to complement their primary skills or party composition.The passive skill tree in Path of Exile 2 further empowers curse users. Numerous nodes enhance curse effectiveness, increase the number of simultaneous curses, or grant bonuses triggered by cursed enemies. Strategic allocation of points enables players to create powerful combinations, such as amplifying poison damage on cursed targets while simultaneously boosting area-of-effect spell potency. Proper planning ensures that curse builds remain effective from early leveling to endgame content, providing a rewarding progression curve.